Topical Anesthetics
Lidocaine PatchLidocaine Patch 5%
Prescription lidocaine patches, the 5 percent patch (Lidoderm and generics) and ZTlido 1.8 percent, relieve the nerve pain that can linger after shingles. Generic 5 percent patches have several makers and ZTlido is quoted as a brand; over-the-counter 4 percent patches are a different product.
This page is general information about a medication and how cash prices for it are set. It is not medical advice and does not replace the label, your prescriber or your pharmacist. How we handle medical information
Generic 5 percent patches rated equivalent to Lidoderm have several makers; the FDA approved a first generic of ZTlido in 2025, but no label for it was on DailyMed when this guide was checked.
About Lidocaine Patch
Lidocaine, a local anesthetic, dampens pain signals from the nerves behind post-herpetic neuralgia, the burning or stabbing pain that can last months or years after shingles. Both prescription products are labeled for that pain only. Up to three patches, cut to size before the liner is removed if needed, go on intact skin over the most painful area once, for up to 12 hours in any 24: 12 hours on, 12 hours off.
Redness, burning or swelling under the patch are common; if irritation occurs, the patch comes off until it settles. Heating pads and electric blankets can raise the amount absorbed. MedlinePlus says not to shower, bathe or swim while wearing the 5 percent patch, while ZTlido allows short showers and baths. Rarely, methemoglobinemia causes blue or gray skin, headache, a fast heartbeat or breathlessness, more often with G6PD deficiency or heart or lung disease.
A used 5 percent patch still holds most of its lidocaine, enough to seriously harm a child or pet that chews it, so new and used patches are kept out of reach. Over-the-counter 4 percent patches are sold under the FDA’s monograph system, not as generics; the labels checked allow one patch at a time from age 12 and warn against heating pads.
Taking Lidocaine Patch
- How to take it
- Apply the prescribed number of patches, three at most, to clean, dry, intact skin over the most painful area for up to 12 hours, then leave the skin bare for 12 hours. Cut patches with scissors before removing the liner. Avoid spots rubbed by tight clothing, keep heat sources off, and wash your hands after handling. Press a lifting ZTlido back down.
- If you miss a dose
- Apply it when you remember, unless the next patch is nearly due; then skip it. Never wear extra patches or keep one on longer.
- Storage
- In the sealed envelope at room temperature, out of reach of children and pets. Fold used patches sticky sides together and discard them out of their reach.
- Interactions to know about
- Class I heart rhythm medicines such as mexiletine add to lidocaine’s effects, and other local anesthetic products add to the total absorbed. Medicines linked to methemoglobinemia, including nitrates and some antibiotics, antimalarials and seizure medicines, raise that risk. Severe liver disease slows lidocaine’s breakdown.
This summarizes the official prescribing information. Your prescriber’s and pharmacist’s instructions, and the leaflet that comes with your medicine, take priority.
Why the cash price for Lidocaine Patch differs from pharmacy to pharmacy
Generic 5 percent patches are rated by the FDA as equivalent to Lidoderm, so a prescription that allows substitution can be filled with whichever generic the pharmacy stocks, and quotes differ by cost and markup. Lidoderm or ZTlido written by name without substitution is priced as a brand.
Quantity drives the total: a carton of 30 lasts a month at one patch a day but ten days at three.
Upload it and licensed pharmacies reply with their own cash price. You pay the pharmacy, not us.
Ways to pay less for Lidocaine Patch without insurance
- Ask the prescriber to allow generic substitution, so a generic 5 percent patch can be dispensed instead of Lidoderm.
- If ZTlido is prescribed, ask whether the 5 percent patch would suit you, since ZTlido is quoted as a brand.
- Ask the prescriber whether an over-the-counter 4 percent patch would be enough for your pain; it follows different directions.
- Upload the prescription to Script Unlock so licensed pharmacies can quote their cash price. You pay the pharmacy directly.
How Script Unlock gets you a cash price for Lidocaine Patch
Prices on this site come from pharmacies responding to a real prescription. We do not publish estimated, average or "typical" prices, because none of those would be your price.
- 1You upload your prescription
A photo of your Lidocaine Patch prescription is enough. Nothing is sold on the site; you are asking pharmacies to quote.
- 2Licensed pharmacies respond
Pharmacies that Script Unlock has verified see the request and each can reply with its own cash price for your exact drug, strength and quantity.
- 3You choose and pay the pharmacy
You compare the responses, pick a pharmacy, and pay that pharmacy directly when you collect. Script Unlock never takes a patient payment and never sets the price.
Questions to ask your pharmacist about Lidocaine Patch
- 1.How many patches can I wear, and for how long?
- 2.Can I cut the patch, and can I shower with it on?
- 3.Is this a generic of Lidoderm, or ZTlido?
- 4.Is it safe with my heart rhythm medicine or other numbing products?
- 5.How do I store and dispose of patches with children or pets at home?
Where Lidocaine Patch fits
Related medications
Sources
Script Unlock is a marketplace that lets licensed pharmacies quote a cash price on your prescription. It does not prescribe, dispense or sell medication, does not process patient payments, and does not give medical advice. Always follow the instructions of your prescriber and pharmacist and read the medication guide supplied with your medicine.